The track leaders, along with their contact information, are:
| Christi Walter | walter@uthscsa.edu | 210-567-3832 |
| Robin Leach | leach@uthscsa.edu | 210-567-6947 |
Genetics Track List
AHUJA, Sunil K., Medicine/Infectious Diseases - Our work is currently focused on understanding the role of the chemokine system and other immune molecules in HIV-1 pathogenesis.
ARAR, Nedal Hamdi, Medicine – Renal Disease.
BAI, Yidong, Cellular and Structural Biology - Mitochondrial, respiratory chain, complex assembly, turnover, copy number control.
BISHOP, Alexander, Cellular & Structural Biology – The research of the laboratory is aimed at understanding the contribution of different genes to genomic instability and the role of such instability in development, aging and carcinogenesis.
BOYER, Thomas G., Molecular Medicine - We employ biochemical, molecular, and cell biological approaches to study the regulation of eukaryotic RNA polymerase II transcription.
CHEN, Shuo, Pediatric Dentistry – None Available
CODY, Jannine D., Pediatrics - syndromes of chromosome 18 (18q-, 18p-, Tetrasomy 18p, Ring 18 & Trisomy 18). We are interested in understanding the molecular basis, clinical and educational features as well as the natural history of individuals with these syndromes.
COLETTA, Dawn K., Medicine – Diabetes – None Available.
DAHIA, Patricia, Medicine - The laboratory's main focus is the utilization of genomics-based approaches to study the genetics of cancer, to characterize interactions between oncogenic pathways, and to identify novel cancer-related genes.
ESCAMILLA, Michael A., Psychiatry - Population Genetics, Linkage Disequilibrium Mapping, Genetics of Bipolar Disorder and Schizophrenia, Genetics of Mood Disorders, and Substance Abuse Comorbidity in Bipolar Disorder.
FERRY, Robert Jean Jr., Pediatrics - Etiopathophysiology of diabetes mellitus and its complications. Basic studies interface with patient-oriented research in the disorders of insulin secretion.
FURMAGA, Wieslaw B., Pathology – Clinical Chemistry/Pathology Physiology/Molecular Toxicology/Proteomics.
GAZITT, Yair, Medicine - Mode of action of gemcitabine and taxol. Mechanism of drug resistance in multiple myeloma. Involvement of bcl2 family of proteins and p53 in apoptosis in multiple myeloma.
GIBSON, James B., Pediatrics - Metabolic Genetics.
HARRIS, Stephen E., Periodontics – Bone Morphogenetic Protein and their Expression.
HENDERSON, George I., Medicine/Gastroenterology - The primary objective of my research is to gain a better understanding of the basic mechanisms underlying alcohol and oxidative stress-induced damage to the developing brain.
IMAM, Syed Z., Medicine - The main research goal of my laboratory is to understand the molecular basis of neurodegeneration, which can be implicated to develop therapeutic trials for neurodegenerative diseases.
JOHNSON-PAIS, Teresa L., Pediatrics - Genetics of Cancer - Identification of genetic alterations that play a role in cancer tumorigenesis, especially in urologic cancers. Genetics of Paget's Disease of Bone - Understanding the role of mutant SQSTM1 proteins in familial Paget's Disease of Bone.
KADOSH, David, Microbiology - Major human fungal pathogen Candida albicans. Although present as a commensal in the digestive tract of most healthy people, C. albicans is also capable of causing a wide variety of systemic and mucosal infections. Immunocompromised individuals such as AIDS patients, organ transplant recipients, cancer patients undergoing chemotherapy and recipients of artificial joints and prosthetic devices are particularly susceptible to infection.
KELLER, Charles, Cellular & Structural Biology - Mouse models of rhabdomyosarcoma and medulloblastoma.
KRAIG, Ellen, Cellular and Structural Biology - Effects of aging and infection on immunity and autoimmunity.
LARSEN, Pamela, Cellular and Structural Biology - The focus of the laboratory is on understanding the biological mechanisms for the efficient life maintenance, in development and adulthood in C. elegans. It is generally believed that genetic and environmental manipulations result in life span extension by controlling metabolism and resistance to stress. We are interested in understanding the mechanisms of longevity by both means.
LEACH, Robin J., Cellular & Structural Biology - Using a molecular genetic approach, we are studying a number of common diseases including prostate and testicular cancer, diabetes, schizophrenia and Paget’s disease of the bone.
LEE, Sang, Molecular Medicine - Cancer results from genetic and environmental insults leading to the accumulation of mutations in genes preventing the initiation and the progression of this disease.
LEHMAN, Donna M., Medicine/Epidemiology - Our research efforts are focused on the study of human molecular genetics.
MCEWEN, Donald G., Biochemistry - Genetic and biochemical approaches to signaling pathways.
MOORE, Charleen, Cellular & Structural Biology - research activities have centered on characterizing human cytogenetic abnormalities and carrying out comparative cytogenetics studies in primates and marsupials.
NAYLOR, Susan, Cellular & Structural Biology - In our early studies with chromosome 3, we found that the middle of the short arm of chromosome 3 is frequently deleted in many types of cancer including lung, ovarian, head and neck, and uterine cancer. Using a combination of analysis of tumor samples and a functional assay for tumor suppression, we have limited the region to 80Kb of human DNA.
PADALECKI, Susan S., Urology - Bone is the most common site of metastases for solid tumors such as breast, prostate and bladder cancers. These metastases contribute significantly to the morbidity and mortality of these cancers.
PAVLIN, Dubravko, Orthodontics - The primary research interest is in the regulation of genes for bone cell (osteoblast) markers. In particular, the focus is on molecular mechanisms involved in mechanically-induced regulation of bone cell markers, including the type I collagen, osteocalcin, alkaline phosphatase, bone morphogenetic proteins and homeobox-containing genes.
PENALVA, Luiz O., Children’s Cancer and Research Institute - Dissecting gene expression of tumors and complex tissues with RNA binding proteins.
RANJAN, Ravi, Pharmacology - The genetics of aging in Drosophila and the mechanism of neurotransmitter secretion at the synapse.
REBEL, Vivienne I., Children’s Cancer and Research Institute - elucidating the molecular mechanisms that govern stem cell regulation in vivo. Knowledge about stem cell regulation may also benefit our understanding of cancer cell development.
SCHLABRITZ-LUTSEVICH, Natalia, Ob-Gyn - Interests are comparative aspects of placental structure and function, and fetal growth and development.
SHIREMAN, Paula Kay, Surgery - Study of the basic mechanisms of collateral artery formation in the presence and absence of diabetes. Using a rabbit and mouse hind-limb ischemia model, we can quantitate the number of collateral arteries using arteriography and hemodynamic changes using fluorescent microspheres to measure regional blood flow. Currently we are interested in the role of inflammatory cells in the regulation of collateral artery formation.
SLAGA, Thomas J., Pharmacology - glucocorticoid hormones (GC), very potent inhibitors of physiological DNA synthesis in keratinocytes in vivo.
TOMLINSON, Gail, Pediatrics - Genetic predisposition to cancer, Hepatoblastoma, Hereditary breast cancer, Other Pediatric Tumors, Population-specific aspects of childhood cancer, von Hippel-Lindau disease.
VOGEL, Kristine Susan, Cellular & Structural Biology - Neurofibromatosis Type 1 and Genomic Instability.
WALSS-BASS, M Consuelo, Psychiatry - Role of genetic polymorphisms in risk of Schizophrenia and Bipolar Disorder. Correlation of allelic variations with functionality in relation to schizophrenia pathology. Understanding the molecular mechanisms of schizophrenia.
WALTER, Chris, Cellular and Structural Biology - DNA repair, mutagenesis, mitochondria, transgenic mice, aging, spermatogenic cells.
WHANG, Kyumin, Restorative Dentistry - The major thrust of the research conducted in my laboratory is the development of three-dimensional biodegradable scaffolds for tissue engineering.
YEW, P. Renee, Molecular Medicine - Vertebrate cell cycle regulation, DNA replication initiation, Ubiquitin-mediated proteolysis and signaling, Tumor suppressor function.
Faculty & Staff