M_I_Track_Logo.jpg

Microbiology and Immunology

The Microbiology and Immunology Track focuses on microbial infection, host responses to infection and other aspects of the immune system in health and disease. The faculty members engaged in this track apply state-of-the-art experimental approaches, including genomics, proteomics and bioinformatics, as well as other genetic, biochemical and functional assays to study the regulation, host interactions and pathogenesis of viral, bacterial, fungal and parasitic infections. In addition to mechanisms of host interactions with microorganisms, responses to allergens, tumor and self-antigens are also investigated at the molecular, cellular, tissue and whole-body levels. Students will gain the broad knowledge and skills necessary for future research careers in many different areas of basic and clinical life sciences, including microbial genetics, physiology and pathogenesis, infectious diseases, immune regulation, vaccinology, tumor immunology, autoimmunity and allergy.

The track leaders, along with their contact information, are:

Guangming Zhong  zhongg@uthscsa.edu 
210-567-1169 
Anthony Infante
infantea@uthscsa.edu 
210-567-0510


For more information, click here.


M & I Track Faculty

AHUJA, Sunil, Medicine-Infectious Diseases, UTHSCSA. Key Words: Role of chemokine and chemokine receptors in immune system development, defense against chronic or infectious diseases, and HIV-1 pathogenesis 

BASEMAN, Joel B., Microbiology & Immunology, UTHSCSA. Key Words: Host-mycoplasma interplay; Mechanisms of cytadherence; Invasion; Intracellular persistence; Molecular basis of virulence; Toxin-mediated cytopathology; Gene regulation 

BERTON, Michael T., Microbiology & Immunology, UTHSCSA. Key Words: Cytokine and Toll-like receptor signaling; immunity to infection; Francisella tularensis; interleukin-4 

BOSE, Santanu, Microbiology & Immunology, UTHSCSA. Key words: Innate immunity against respiratory RNA viruses; virus-host interactions; identification and characterization of anti-viral factors; anti-viral signaling pathways; development of anti-cancer therapeutics with oncolytic viruses 

CLARK, Robert E., Medicine-VP for Clinical Research, UTHSCSA. Key Words: Inflammation; phagocytosis; neutrophil; NADPH oxidase (NOX); oxygen radicals; superoxide; signal transduction; transcription; biology of aging; neurodegenerative diseases

COLE, Garry T., Biology, UTSA. Key Words: medical mycology; animal models of mycoses; vaccine development; fungal virulence; transcription profiling; proteomics 

CURIEL, Tyler, Med/Hematology & Med Oncology, UTHSCSA. Key Words: Dendritic cell; Regulatory T cell; Chemokines; Tumor immunity; Immune dysfunction 

DHANDAYUTHAPANI, Subramanian Microbiology & Immunology, RAHC, UTHSCSA. Key Words: bacteria; tuberculosis; virulence; vaccine; signal transduction; stress response; mycoplasma

DUBE, Peter H., Microbiology & Immunology, UTHSCSA. Key Words: Bacterial host-pathogen interaction in vivo; inflammation; cytokine response; Yersinia; asthma, inflammatory T-cell responses 

GAO-Shou-Jiang, Pediatrics, CCRI, UTHSCSA. Key Words: KSHV/HHV8; Kaposi's sarcoma; AIDS-related malignancies; Angiogenesis; Inflammation; microRNA; Herpesvirus; Latency and Reactivation

GIAVEDONI, Luis D., Virology & Immunology, SNPRC, SFBR. Key Words: Innate and adaptive immune responses to vaccines and viral infections; SIV pathogenesis and vaccine development

HALDENWANG, William G., Microbiology & Immunology, UTHSCSA. Key Words: Microbial Genetics; Bacillus; RNA Polymerase; Sporulation; Transcription Regulation; Bacterial Stress Responses; Microbial Development

INFANTE, Anthony J., Pediatrics, UTHSCSA. Key Words: Primary immune deficiency diseases; T-cell receptor repertoire development; immune reconstitution; autoimmune diseases; myasthenia gravis 

IZUMI, Kenneth M., Microbiology & Immunology, UTHSCSA. Key Words: Epstein-Barr virus transformation of B-lymphocyte growth; viral oncoprotein signal transduction; nuclear transactivation 

KADOSH, David , Microbiology & Immunology, UTHSCSA. Key Words: Candida; Transcription; Filamentous growth; Genomics; Fungus; Morphology; Virulence; Infection

KLOSE, Karl E., Biology, UTSA. Key Words: Molecular mechanisms of Vibrio cholerae and Francisella tularensis pathogenesis; transcription regulation; biodefense and food-borne disease vaccine development 

KOLODRUBETZ, David J. , Microbiology & Immunology, UTHSCSA. Key Words: Bacterial genetics; virulence mechanisms in periodontal pathogens; transcriptional regulation; function of microbial surface layer proteins

KRAIG, Ellen B., Cellular & Structural Biology, UTHSCSA. Key Words: Molecular immunology; autoimmunity; bacterial pathogenesis 

KROLICK, Keith A., Microbiology & Immunology, UTHSCSA. Key Words:  acetylcholine receptor; autoimmune disease susceptibility; IL-4 receptor; iNOS; muscle; muscle fiber type; myasthenia gravis; rat disease model

LANFORD, Robert E., Virology & Immunology, SNPRC, SFBR. Key Words: Molecular biology and pathogenesis hepatitis B virus, and hepatitis C virus 

MCMANUS, Linda M., Pathology, UTHSCSA. Key Words: inflammation; tissue regeneration; pathobiology

MELBY, Peter C., Medicine-Infectious Diseases, VA, UTHSCSA. Key Words:  Immunopathogenic mechanisms and protective immunity; in leishmaniasis

ORIHUELA, Carlos J., Microbiology & Immunology, UTHSCSA. Key Words: Streptococcus pneumonia; Aging; Pneumonia; Lungs; Virulence; Bacterial pathogenesis

PATTERSON, Jean L., Virology & Immunology, SNPRC, SFBR. Key Words: Molecular Biology of RNA viruses and development of Anthrax therapeutics

TEALE, Judy M., Biology, UTSA. Key Words: Immunobiology, immunology and pathogenesis of neurocysticercosis, immune response to Francisella tularensis

WICKES, Brian L., Microbiology & Immunology, UTHSCSA. Key Words: Medical mycology; Aspergillus Cryptococcus and Candida molecular biology; fungal mating systems; fungal molecular identification

XIANG, Yan, Microbiology & Immunology, UTHSCSA. Key Words: Poxvirus pathogenesis and immune modulation; virus-host interactions; protein structure-function 

ZHONG, Guangming, Microbiology & Immunology, UTHSCSA. Key Words: Microbial pathogenesis; microbial interactions with host cells; immunity and microbial immune evasion; diagnosis and vaccine development; Chlamydia trachomatis; Chlamydia pneumoniae